In recent years, many networks, organizations, coalitions, and collaborations have emerged to support regeneration at a bioregional and “landscape” scale. We believe we are at a moment when there is a need for and widespread interest in possibilities for “radical collaboration” so that these diverse initiatives can begin to function as a global ecosystem--one that can navigate the complexity of working across scales, across the private, public, and grassroots domains, and across the many interconnected systems where regenerative work is being imagined and enacted. The Summit offers an open and flexible invitation for participants to explore four connected contexts for this radical collaboration: How global networks can support one another How bioregions can support one another How funding innovation can support bioregional scale regeneration How we can support our emotional, physical and spiritual resilience as individuals grappling with the existential threats of the climate crisis, biodiversity loss, economic and social injustice, political fragmentation, and other dimensions of Collapse.